Unless someone invents time
travel, you can’t reverse the flow of time and become younger.
However, with the wide array of dermatologic treatments available today,
you can remove many of the effects of aging and photoaging. You can’t
become younger, but you can look younger and more attractive by working
with a dermatologist to choose the skin rejuvenation treatment that is
right for you.
This segment of AgingSkinNet
provides a description and discussion of the major treatments available
today for skin rejuvenation. Sometimes two types of treatment may be
combined to make each more effective.
Treatments discussed in this
segment:
More information regarding facial
skin rejuvenation procedures is available on the Web site of the
American Society for Dermatologic Surgery. Monthly Updates
of AgingSkinNet will have more information about procedures as it
becomes available.
Dermatologic Medical Skin
Rejuvenation
Topically-applied treatments are
usually most effective when skin manifestations of aging and photoaging
are superficial to moderate:
-
Tretinoin, a substance in the
vitamin A family, has been shown to reduce fine wrinkles, splotchy
pigmentation, and rough skin associated with chronic sun exposure.
Tretinoin cream 0.02% and 0.05% are the only prescription treatments
approved by the Food and Drug Administration (FDA) for these
indications. Other available forms of tretinoin are indicated for the
treatment of acne. Talk to your dermatologist about which tretinoin
formulation may be right for you.
-
Alpha-hydroxy acids (AHSs) may
be used alone or in combination with tretinoin to treat mildly damaged
skin. AHAs are derived from fruit and dairy products.
-
Over-the-counter products
containing retinols (of the vitamin A family), AHA, anti-oxidants and
moisturizing agents may temporarily improve the appearance of fine
lines and wrinkles.
-
Topical antioxidants, especially
vitamins C and E, function to help cells repair damage caused by
ultraviolet radiation and smoking.
 |
 |
| Before |
After |
|
These untouched photographs show this woman
before and after six months of treatment with tretinoin cream 0.05%. Her
reduction in fine lines and wrinkles is characteristic of a more
dramatic improvement experienced during clinical trials. Individual
results may vary.
|
Dermatologic Surgical Skin
Rejuvenation
Chemical Peeling
Chemical peeling,
also called chemexfoliation or dermapeeling, is a facial skin
rejuvenation procedure that does what its name implies—it peels the
skin. Its use is usually in the treatment of superficial to moderate
photoaging skin damage. Mild chemical peels can be applied to people in
their 20s, to prevent effects of aging from becoming apparent too early
in life.
In a chemical peeling treatment, a
chemical solution is applied to facial skin, causing the skin to blister
and peel off over a period of days. As the treated skin blisters and
peels, new skin forms to take its place. The new skin is usually
smoother and less wrinkled than the old skin.
A mild chemical peel is usually
all that is necessary to treat fine lines and wrinkles around the eyes
and mouth. Patients with minimal skin damage often respond best to a
series of light peels in combination with a skin care program including
retinoids and a sunscreen protection program. A medium-depth peel is
often more effective for patients with moderate skin damage, including
age spots, freckles and actinic keratoses. A medium-depth peel
may be combined with another treatment such as laser resurfacing
to achieve maximum effectiveness.
Depending on the objectives of the
treatment as determined jointly by the patient and dermatologist, the
condition and type of the patient’s skin, and the degree of skin
damage, the dermatologist by performing dermatologic surgery
individualizes the strength of the chemical solution and the depth of
the peel. Peeling solution may include one or more chemicals such as
alpha-hydroxy acids, trichloroacetic acid, or carbolic acid. The
procedure can be performed in the dermatologist’s office, or in an
outpatient surgery center. In addition to skin rejuvenation, chemical
peeling is effective in reduction of some acne scars. Peeling does not
remove deep scars.
The immediate after-effect of a
chemical peel is similar to a sunburn. After a mild or superficial peel,
redness and scaling of the skin last 3 to 5 days. Medium-depth or deep
peeling can result in redness, swelling, blistering and peeling for 7 to
14 days. Medications are prescribed to alleviate discomfort.
Overexposure to sun must be avoided for a period of time to prevent sun
damage while the new skin is susceptible to injury.
Chemical peeling is effective only
for surface skin damage. Effects of aging in deeper tissues, such as
sagging jowls and drooping eyelids, must be addressed by other
procedures that can be recommended by your dermatologic surgeon.
Soft-tissue Augmentation
In soft-tissue
augmentation,
a substance that is compatible with the patient’s body tissues is
injected under the skin to elevate irregularities such as wrinkles, pits
and scars. The substances used for injection are primarily:
-
Collagen—a
fibrous protein substance of all human and animal tissue. It gives
toughness and structure to skin, bones, and ligaments. Most of the
collagen used for soft-tissue augmentation is derived from cattle.
However, for people who are allergic to bovine (cow-derived) collagen,
collagen or collagen-related substances may be self-donated by the
patient or obtained from a tissue donor. The dermatologist tests the
patient prior to collagen injection to determine if the patient is
allergic to bovine collagen. Collagen injection is usually given in a
series of treatments, until the desired effect of "filling
out" a wrinkle or depression is achieved. A local anesthetic
minimizes discomfort from the injection needle. The effects of
collagen injection may last for 3 to 12 months.
-
Self-donated body fat. Fat is
harvested from the patient’s own body and prepared for the procedure
called microlipoinjection. This fat-transfer procedure is sometimes
called "body sculpturing". The injected body fat is used to
replace fat lost from under the skin in the aging process. Defects
improved by microlipoinjection include creases around the nose, mouth
and chin, and the "drawn look" created by loss of fat pads
in the cheeks. The improvements in appearance vary between patients.
Some follow-up treatments may be necessary. Microlipoinjection is
performed in an outpatient clinic. An after-effect of tissue swelling
or bruising fades in a few hours to a few days.
Botulinum Toxin
Dermatologists have harnessed the
potent biological effects of botulinum toxin to dramatically improve
effects of aging such as frown lines, crows feet, and facial wrinkles.
Botulinum toxin is the powerful agent of botulism food poisoning, but
botulism cannot be contracted from cosmetic use of botulinum toxin. The
toxin’s biological effects in food poisoning are to block nerve
impulses transmitted from the brain to muscles, causing generalized
paralysis including paralysis of muscles used in breathing.
Dermatologists use purified
botulinum toxin in very tiny amounts to inject into a targeted facial
muscle. The resulting nerve blockade of that muscle causes a local
immobilization of muscle movement. This immobilization prevents
"crinkling" and "wrinkle" lines from forming when
the patient frowns or squints. Results of treatment last 3 to 4 months.
To be maximally effective, treatment with botulinum toxin is repeated
over several sessions and is combined with a program of muscle
behavioral training to minimize "wrinkling" facial
expressions. Botulinum toxin treatment may be used in combination with
other procedures for facial rejuvenation to achieve a more lasting
effect. A botulinum toxin treatment is accomplished in about 30 minutes
in a dermatologist’s office
Dermabrasion
Dermabrasion
is a treatment with many applications in dermatology and dermatologic
surgery, from removal or reduction of acne and chicken pox scars to
facial skin rejuvenation. The procedure, sometimes called surgical skin
planing, consists of planing off the surface layer of skin with a
rapidly rotating brush. The planing action removes the skin surface, and
a new layer of skin grows to replace the skin removed. The principal
after-effect is redness of the skin similar to a severe sunburn;
medications are prescribed to alleviate discomfort. Healing usually is
complete in about 10 days. Patients must avoid sunlight for 3 to 6
months after treatment. A technique that removes less surface skin is
called microdermabrasion; it is used most often for superficial skin
defects and may be repeated at intervals.
Each potential candidate for
dermabrasion needs thorough evaluation by a dermatologist to make
certain that dermabrasion is the correct procedure for that individual
and that the patient fully understands possible after-effects. For
example, pigmented skin may be permanently lightened in the area of
dermabrasion, and a person prone to form keloids after skin injury could
be at risk for scarring. Post-procedure treatments are available to
minimize most after-effects. Dermabrasion may be combined with other
procedures such as soft-tissue augmentation to maximize
effectiveness.
Laser Skin Resurfacing
The use of lasers in dermatology
has advanced rapidly over the past 30 years. Today, lasers have a broad
range of dermatologic applications, including:
-
removal or improvement of
wrinkles, lines and other effects of aging and photoaging
-
treatment of superficial brown
pigmented lesions such as age spots, and deep pigmented lesions such
as port wine stains and birthmarks
-
removal or improvement of scars
-
removal of some skin cancers
-
removal or improvement of
vascular moles
-
removal of tattoos
-
removal of warts
-
removal of unwanted hair
The principal applications of
lasers in facial skin rejuvenation are reduction or removal of wrinkles,
lines and age spots, to "resurface" the skin.
The laser (Light Amplification
by the Stimulated Emission of Radiation) is a
"light pump". It applies principles of radiation
physics to narrowly segregate light of selected wavelength and
"pump" the light radiation to high intensity. These beams of
selected wavelength can be varied in intensity and in the duration of
emitted pulses.
For example, powerful, rapid
pulses of the infrared-wavelength carbon dioxide laser can vaporize
targeted skin. The pulses of the carbon dioxide laser can be directed
toward resurfacing skin without bleeding. The benefits of laser skin
resurfacing include bloodlessness, plus:
-
reduced risk of infection
-
precisely controlled surgical
effects
-
one-day outpatient treatment in
many instances
After-effects and recovery times
vary with different laser procedures. A dermatologist will explain the
risks, after-effects and benefits of recommended procedures.
Lasers are powerful instruments
and laser surgery should be performed only by a dermatologist or
dermatologic surgeon with experience in the procedure. To learn more
about lasers and laser surgery, go to the Web site of the American
Society for Dermatologic Surgery.
Electrosurgical Resurfacing
An alternative to laser skin
resurfacing is electrosurgical resurfacing, also called "cold
ablation." This technique uses a micro-electrical radio frequency
to deliver a pulse of energy to the skin, removing or improving
superficial to moderate skin damage. The procedure has few
after-effects, and recovery from mild to moderate swelling is usually
complete within a month. Electrosurgical resurfacing offers the
advantage of being applicable to most skin types and colors, without
loss of skin pigmentation.
Superfluous Hair Removal
Removal of superfluous hair may
contribute to overall improved appearance, with or without concomitant
facial skin rejuvenation. In women, especially, hair on the chin, over
the upper lip, or on arms and legs can create an appearance of older age
or masculinization. Traditional methods of dealing with superfluous hair
include: (1) bleaching with hydrogen peroxide to make the hair less
visible, (2) shaving to temporarily remove hair, (3) plucking hairs, (4)
coating the skin with wax, then removing hair with the waxy coat, (5)
using a chemical depilatory to "dissolve" unwanted hair, and
(6) electrolysis or electrothermolysis to destroy hair follicles for
relatively permanent hair removal.
Chemical depilation of facial skin
may be irritating and should be performed under the guidance of a
dermatologist with a depilating agent prescribed for individual needs.
The safety and effectiveness of
electrolysis or electrothermolysis is dependent upon the training and
skill of the operator and the equipment used. In these methods a fine
electrode is inserted into each hair follicle to destroy the cells from
which new hair could grow.
Laser hair removal has been proven
effective in recent studies. Hair loss for two or more years has been
documented, and may well prove to be long-term or permanent as patients
are followed up for longer periods of time. Laser hair removal in most
current use is accomplished by photothermolysis—using a laser to
generate heat in hair follicles and render them incapable of growing new
hair. Skin color and hair color are among factors that a dermatologist
considers in determining the type of laser to use, duration of
treatment, and number of treatments that may be necessary to accomplish desired results. Side effects of laser hair removal include
post-treatment pain for a few hours to a few days, and skin redness. The
treating dermatologist can prescribe medicines to alleviate the side
effects. Laser hair removal is a procedure that should be performed only
by a dermatologist experienced in the use of lasers.
Non-ablative Skin Treatments
Liposuction
Wrinkles, crease lines and age
spots are visible effects of aging, and unwanted fat deposits are
another. Despite diet and exercise undertaken to keep looking young and
trim, fatty deposits may remain on the face, chin, neck, breast,
abdomen, hips, thighs, buttocks, knees and ankles. A dermatologist
experienced in the procedure can use tumescent liposuction to
remove these localized fat deposits. Tumescent liposuction is performed
only after a full medical evaluation.
This dermatologic surgery is
performed in an outpatient setting, usually under local anesthesia and
anti-bleeding medication. In some cases, ultrasound is used to break
down and liquify fat cells in the area to be treated. Fat is removed
from the targeted area with a vacuum inserted through an incision in the
skin. Many patients do not require postoperative pain medication. It is
usually possible for the patient to resume physical exercise 3 to 7 days
after the procedure. Liposuction is not a substitute for diet, exercise
or weight reduction. It complements other efforts to keep a young and
trim look. Go to the Web site for the American Society for
Dermatologic Surgery for more information about liposuction.
Surgical Excision
Sometimes facial skin rejuvenation
cannot be accomplished to the patient’s satisfaction by removal of
surface defects. Long-term effects of gravity may affect deeper layers
of tissue, with resulting sags in eyelids, forehead, cheeks, shin, and
areas around the mouth. In these instances, a dermatologic surgeon
should be consulted regarding the possibility of surgical procedures:
(eyelid surgery) to correct "droopy" eyelids by removing
excess fat pads and skin
brow lift to reduce severs lines
in the forehead and raise the eyebrows
rhytidectomy
(fact lift) to tighten and trim excess skin on cheeks, chin, neck, and
around the mouth
Go to the Web site for the American
Society for Dermatologic Surgery for more information about facial surgery.