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Risk
Factors Update
Dysplastic Nevi (Atypical Moles) As Risk Factors for Melanoma
The word "dysplastic" has a specific meaning in medicine:
alteration in size, shape and organization of cells.
A dysplastic nevus (atypical mole) is a nevus that is unusual
in appearance due to its size, shape or color. Dysplastic nevi are
usually larger than common moles, with indistinct borders or a fried-egg
appearance with distinct borders, and may range in color from tan to
dark brown.
Dysplastic nevi appear on the skin beginning around the middle of the
first decade of life.
It is important to know about dysplastic nevi because they can be a
"marker" for increased melanoma risk. The risk is increased
when (1) there is a family history of melanoma, (2) when there are
numerous dysplastic nevi, and (3) when the skin is light-colored and
heavily freckled due to excessive sun exposure.
See below for color photos of dysplastic
nevi and dysplastic nevi biopsy sections.
Dysplastic Nevi
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| Multiple dysplastic nevi |
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| Dysplastic nevus, Atypical nevus |
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| Dysplastic nevus |
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| Dysplastic nevus |
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| Biopsy section, dysplastic nevus |
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| Biopsy section, dysplastic nevus |
Slides used with permission of the American Academy of Dermatology
National Library of Dermatologic Teaching Slides and the Sulzberger
Institute for Dermatologic Education. |