What is Psoriasis?

Psoriasis is a chronic, genetic, noncontagious skin disorder that appears in many different forms and can affect any part of the body, including the nails and scalp. Psoriasis is categorized as mild, moderate, or severe, depending on the percentage of body surface involved and the impact on the patient's quality of life (QoL). Psoriasis may be one of several types: plaque psoriasis, pustular psoriasis, erythrodermic psoriasis, guttate psoriasis or inverse psoriasis. A dermatologist can help you to determine what type of psoriasis you may have. 

Types of Psoriasis
Although psoriasis may affect any area of the body, it is most commonly found on the scalp, elbows, knees, hands, feet, and genitals. Plaque psoriasis, the most common type of the disease, is characterized by raised, thickened patches of red skin covered with silvery-white scales. Other types of psoriasis are characterized by different signs and symptoms. For example, pustular psoriasis is characterized by pus-like blisters, erythrodermic psoriasis is characterized by intense redness and swelling of a large part of the skin surface, guttate psoriasis is characterized by small, drop-like lesions, and inverse psoriasis is characterized by smooth red lesions in the folds of the skin. 

Although psoriasis may be almost unnoticeable in its early stages, patients often report an itching and/or burning sensation as the disease progresses. In particular, plaque psoriasis usually begins with small red bumps on the skin that progress to bigger, scaly patches that may become itchy and uncomfortable. As the scales accumulate, pink to deep red plaques with a white crust of silvery scales appear on the skin surface. The pictures below depict various types of psoriasis.


Psoriasis


Plaque Psoriasis


Psoriasis

Psoriasis

Guttate Psoriasis

Pustular Psoriasis

Pustular Psoriasis

The Psoriatic Nail

About 50 percent of persons with active psoriasis have psoriatic changes in fingernails and/or toenails. In some instances psoriasis may occur only in the nails and nowhere else on the body. Psoriatic changes in nails range from mild to severe, generally reflecting the extent of psoriatic involvement of the nail plate, nail matrix (tissue from which the nail grows), nail bed (tissue under the nail), and skin at the base of the nail. Damage to the nail bed by the pustular type of psoriasis can result in loss of the nail.

Nail changes in psoriasis fall into general categories that may occur singly or all together:

  • The nail plate is deeply pitted, probably due to defects in nail growth caused by psoriasis.
  • The nail has a yellow to yellow-pink discoloration, probably due to psoriatic involvement of the nail bed.
  • White areas appear under the nail plate. These are air bubbles marking spots where the nail plate is becoming detached from the nail bed (onycholysis). There may be reddened skin around the nail.
  • The nail plate crumbles in yellowish patches (onychodystrophy), probably due to psoriatic involvement in the nail matrix.
  • The nail is entirely lost due to psoriatic involvement of the nail matrix and nail bed.

The following four photos illustrate psoriatic changes in nails:


Psoriasis of fingernails.


Psoriasis of fingernails.


Onycholysis in psoriatic fingernails.


Pustular psoriasis on toenails and foot.

(Photos used with permission of the American Academy of Dermatology 
National Library of Dermatologic Teaching Slides and the Sulzberger Institute for Dermatologic Education)

Psoriasis of the nails can resemble other conditions such as chronic infection or inflammation of the nail bed or nail fold. Psoriasis of the toenails can resemble chronic fungal infection of the nails.

A person with psoriatic nails should avoid any injury—bumps, scrapes, etc.—that may trigger a worsening of psoriasis (Koebner’s phenomenon). Nail psoriasis is treated by the dermatologist as part of the overall treatment of the disease.

Nail psoriasis is frequently associated with psoriatic arthritis.

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This information sponsored by an unrestricted educational grant from Amgen, Inc.




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