Used to treat:
Atopic dermatitis (severe)
Cyclosporine has been used for many
years to treat severe atopic dermatitis that does not respond to
other treatment. In clinical trials, patients taking cyclosporine
have experienced prompt relief, but most see a rapid relapse after
stopping the medication. Long-term maintenance therapy tends to keep
atopic dermatitis in remission.
What it does: Cyclosporine
suppresses the patientís T cells (a type of white blood cell), which
prevents the immune system from overreacting. Without this reaction,
atopic dermatitis does not flare.
Potential side effects limit the use of cyclosporine. These include
increased risk of developing cancers, tingling or burning sensations
in the arms or legs, fatigue, abdominal upset, musculoskeletal or
joint pain, and headache.
How to use: Available in capsule
or liquid form, cyclosporine should be taken only as prescribed.
Topical preparations of cyclosporine are not available because the
medication cannot penetrate the skin.
Before taking cyclosporine, a patientís kidney function and blood
pressure must be checked. If cyclosporine is prescribed, these will
be monitored regularly during therapy.
Other key facts: Cyclosporine is
a potent medication that suppresses the immune system. The U.S. Food
and Drug Administration (FDA) has approved it for preventing organ
rejection following a transplant operation. When used along with
other medications, cyclosporine proves very effective in preventing
organ rejection. The medication also helps control severe psoriasis
and rheumatoid arthritis.
All content solely
developed by the American Academy of Dermatology