Interferon Gamma

Used to treat:

Atopic dermatitis (severe, unremitting)

What it does: Interferon gamma stimulates the body’s immune system.

While the body naturally produces interferon gamma to fight infections and tumors, research shows that people with atopic dermatitis produce lesser amounts. To find out if treatment with interferon gamma could correct this imbalance and reduce the severity of the atopic dermatitis, studies have been conducted.

In clinical trials, patients with severe, unremitting atopic dermatitis who received recombinant interferon-gamma often had significant decreases in redness, swelling, itch, dryness, thickening skin, and the amount of skin covered by atopic dermatitis. While the results are promising, more research is needed.

How to use: Injections should be given as prescribed.

Chang TT et al. “Atopic dermatitis: the role of recombinant interferon-gamma therapy.” American Journal of Clinical Dermatology. 2002; 3(3):175-183.

Hanifin JM et al. “Recombinant interferon gamma therapy for atopic dermatitis.” Journal of the American Academy of Dermatology. 1993. February;28(2 Pt 1):189-197.


All content solely developed by the American Academy of Dermatology

While not approved by the U.S. Food and Drug Administration (FDA) for treating atopic dermatitis, injections of interferon gamma have provided significant relief for select patients with severe, unremitting atopic dermatitis.





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Page last updated 4/3/07

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